Fascial Innervation: A Systematic Review of the Literature

Written in 2022 by: Vidina Suarez-Rodriguez, Caterina Fede, Carmelo Pirri  Lucia Petrelli, Juan Francisco Loro-Ferrer, David Rodriguez-Ruiz, Raffaele De Caro, Carla Stecco

The human body is a marvel of interconnected systems, and the fascia stands out as a vital component. Fascia, a type of connective tissue, plays a significant role in our body’s function. This article delves into the innervation of the fascia, shedding light on the latest findings from a systematic review of the literature.

The Fascia and Its Importance

Fascia is a connective tissue that wraps around most structures within the human body, including muscles, blood vessels, and nerves. It acts as a biological fabric, ensuring smooth movement and function. Its innervation, or the distribution of nerve fibers, plays a crucial role in pain perception and proprioception (the body’s ability to sense its position).

Research Methodology

A systematic review was conducted, focusing on studies from 2000 to 2021, available in English and Spanish. The primary criteria for inclusion were studies involving animals and humans that explored any nerve receptor in the fascia. After a rigorous selection process, 23 articles were thoroughly reviewed.

Key Findings

Diverse Sample: The studies reviewed involved various subjects, including rats, mice, horses, and humans. Some studies were conducted on human cadavers, while others involved live humans.

Fascial Innervation: The fascia is profusely innervated. It contains both proprioceptors (sensors that detect body position) and nociceptors (pain receptors). The density and/or length of these nociceptors increase under pathological conditions.

Clinical Implications: The findings from these studies contribute significantly to our understanding of fascial innervation. Recognizing the role of nerve receptors in the fascia can pave the way for improved pain management and therapeutic approaches.

Conclusion

The fascia’s innervation plays a pivotal role in how we perceive pain and understand our body’s position. This systematic review offers valuable insights into the fascia’s intricate nerve network, emphasizing the need for further research in this area. A deeper understanding of fascial innervation can lead to better therapeutic strategies for pain management.