Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis, 2018

Topics: Sepsis, Severe sepsis, Sepsis management, Vitamin C, Ascorbic acid, Meta-analysis

Authors: Jing Li


Two recent publications by Sheikh and Horner and Teng et al. reviewed studies on incorporating vitamin C to treat septic patients; however, a meta-analysis was not offered in either report. This commentary extends both reviews by integrating a meta-analysis and sharing aggregated results. Pooled analyses demonstrated a marked reduction in mortality and duration of vasopressor administration in the group with the use of vitamin C.

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